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Mar. 1, 2026

High-Dose Influenza Vaccination in Atherosclerotic Cardiovascular Disease

A Multinational Pooled Analysis of DANFLU-2 and GALFLU (FLUNITY-HD)

Manan Pareek, Niklas Dyrby Johansen, Daniel Modin et al. - JACC

This multinational pooled analysis of the DANFLU-2 and GALFLU trials evaluated the effect of high-dose versus standard-dose influenza vaccination on cardiovascular outcomes in patients with atherosclerotic cardiovascular disease, addressing whether enhanced immunogenicity translates to better cardiovascular protection.

Summary

Publication date: Available online 18 February 2026Source: JACC