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Mar. 5, 2026

Oral PCSK9 inhibitor enlicitide lowers LDL cholesterol levels in phase 2 trial.

Xiulin Koehler - Nature cardiovascular research

This phase 2 trial of enlicitide, an oral PCSK9 inhibitor, showed significant LDL cholesterol reduction. As the first oral PCSK9 inhibitor in clinical development, enlicitide could dramatically expand access to advanced lipid-lowering therapy.