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The Pulse of Primary Care - EPCCS Summit 2026
Talking to Patients About Statins: Why Most Reported Symptoms Aren't Causal
GPcardio and ACC’s NCD Academy Join Forces to Strengthen Primary Care in Cardiovascular Disease Prevention
Sex Differences and Trends in Cardiovascular Risk Management: Insights from a Long-Term Primary Care Study
Primary Prevention of Atherosclerotic Cardiovascular Disease (ASCVD) in Primary care: A Systematic Review of Guidelines
Study on Cardiovascular Risk Factors and Primary Care Utilization in Spain
Global Insights from the INTERASPIRE Study: Mapping Lipoprotein(a) Prevalence in Coronary Heart Disease Across Six WHO Regions
Web app effective in determining access to statins without a prescription
Slides | Take home messages of EPCCS Guidance on 'Managing elevated lipids in primary care'
Lečenje povišenih lipida u primarnoj zdravstvenoj zaštiti (PZZ)
Managementul dislipidemiei în asistența medicală primară
Managing elevated lipids in primary careManaging elevated lipids and statins – the good, the bad and the ugly?
Slides | Lipid-lowering: the evidence, the guidelines, the clinical reality
Lipid Management: What do the guidelines say and what are the implications for primary care?Controversies in Lipids – is the role of statins now clear, are there alternatives, and what’s in the pipeline?The 2025 VA/DoD clinical practice guideline on lipid management introduces updated cardiovascular risk assessment tools, including the PREVENT calculator, one-time lipoprotein(a) testing, and…
Modern Lipid Management for ASCVD Prevention in Primary Care.
This narrative review outlines the evolving landscape of lipid management for atherosclerotic cardiovascular disease (ASCVD) prevention in primary care and cardiology. Beyond traditional risk scores…
atorvastatin 40 mg in healthy adults over 70 prevents 30 percent of cardiovascular events but does not extend disability-free survival
The trial the primary-care question has waited for: 9,971 healthy Australians aged 70 and over (mean 74.7, 52 percent women) randomised to atorvastatin 40 mg or placebo, median follow-up 5.9 years…
evolocumab in the cath lab gets 82 percent of infarct patients to LDL target within a year, without a demonstrable clinical difference
International open-label phase 4 trial: 2,161 patients with high-risk acute MI undergoing PCI, evolocumab 140 mg every two weeks for one year with the first dose given before PCI, versus standard…
what STAREE will and will not answer
STAREE randomised almost 10,000 healthy Australians aged 70 and over to atorvastatin or placebo, with disability-free survival as its primary endpoint. Presented in Hot Line 2 at ESC Congress 2026…
target all atherogenic lipoproteins.
Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of morbidity and mortality in diabetes, partly driven by dyslipidaemia. Although LDL cholesterol (LDL-C) is the primary…
The combined value of lipoprotein(a) [Lp(a)] and high-sensitivity CRP (hsCRP) in primary prevention among people without standard modifiable risk factors (SMuRF-less: no smoking, obesity…
Current genetic testing for coronary artery disease (CAD) mainly targets monogenic variants in severe hypercholesterolaemia. GenProbCAD combines monogenic pathogenic variants with polygenic risk…
a cis-Mendelian randomization study.
Cis-Mendelian randomisation study using individual-level data from UK Biobank, Lifelines, and publicly available GWAS sources, examining 13 lipid-related drug targets (including ACLY, ANGPTL3/4…
Heart review of lipid-related cardiovascular risk beyond LDL cholesterol. While LDL lowering has been the dominant target for decades, mechanistic, observational, and genetic studies support a causal…
Results From a Randomized, Single-Blind, Placebo-Controlled Phase 1 Trial in Treatment-Naive Patients.
Phase 1 randomised, single-blind, placebo-controlled trial of laroprovstat (AZD0780), the first oral small-molecule PCSK9 inhibitor. Unlike injectable PCSK9 antibodies, laroprovstat does not block…
An Updated Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.
Systematic review and dose-response meta-analysis of 38 randomised trials (52 comparisons, n=2,095) on the effect of whole dietary pulses on lipid targets. Median duration 6 weeks, median dose 130…